Evaluating the Effectiveness and Cost-Effectiveness of Seizure Dogs in Persons With Medically Refractory Epilepsy in the Netherlands: Study Protocol for a Stepped Wedge Randomized Controlled Trial (EPISODE)

@article{Wester2020EvaluatingTE,
  title={Evaluating the Effectiveness and Cost-Effectiveness of Seizure Dogs in Persons With Medically Refractory Epilepsy in the Netherlands: Study Protocol for a Stepped Wedge Randomized Controlled Trial (EPISODE)},
  author={Val{\'e}rie Wester and Saskia de Groot and Tim A. Kanters and Louis Wagner and Jacqueline Ardesch and Isaac Corro Ramos and Marie-Jos{\'e} Enders-Slegers and M. de Ruiter and Saskia le Cessie and Jeanine Los and Grigorios Papageorgiou and Job van Exel and Matthijs M. Versteegh},
  journal={Frontiers in Neurology},
  year={2020},
  volume={11}
}
Background: Epilepsy is associated with a high disease burden, impacting the lives of people with epilepsy and their caregivers and family. Persons with medically refractory epilepsy experience the greatest burden, suffering from profound physical, psychological, and social consequences. Anecdotal evidence suggests these persons may benefit from a seizure dog. As the training of a seizure dog is a substantial investment, their accessibility is limited in the absence of collective reimbursement… 

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