Evaluating statistical analyses and reproducibility of microbial mutagenicity assays.

@article{Chu1981EvaluatingSA,
  title={Evaluating statistical analyses and reproducibility of microbial mutagenicity assays.},
  author={K. C. Chu and Kirti M. Patel and Alice H Lin and Robert E. Tarone and M S Linhart and Virginia C Dunkel},
  journal={Mutation research},
  year={1981},
  volume={85 3},
  pages={119-32}
}
The NCI/NTP has completed the first phase of a 4-laboratory study on the reproducibility of testing chemicals for mutagenicity in the Salmonella/microsome assay. This paper is a report of the statistical analysis of some of that data. This analysis involved (1) identifying and removing spurious data; (2) determining the adequacy of the remaining data in making a decision on the mutagenicity of the test chemical; (3) performing the statistical tests; and (4) interpreting the results. Using this… CONTINUE READING

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