Evaluating hepatocellular carcinoma cell lines for tumour samples using within-sample relative expression orderings of genes.

@article{Ao2017EvaluatingHC,
  title={Evaluating hepatocellular carcinoma cell lines for tumour samples using within-sample relative expression orderings of genes.},
  author={Lu Ao and You Guo and Xuekun Song and Qingzhou Guan and Weicheng Zheng and Jianping Zhang and Haiyan Huang and Yi Zou and Zheng Guo and Xianlong Wang},
  journal={Liver international : official journal of the International Association for the Study of the Liver},
  year={2017},
  volume={37 11},
  pages={
          1688-1696
        }
}
BACKGROUND & AIMS Concerns are raised about the representativeness of cell lines for tumours due to the culture environment and misidentification. Liver is a major metastatic destination of many cancers, which might further confuse the origin of hepatocellular carcinoma cell lines. Therefore, it is of crucial importance to understand how well they can represent hepatocellular carcinoma. METHODS The HCC-specific gene pairs with highly stable relative expression orderings in more than 99% of… CONTINUE READING
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