Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strains

@inproceedings{Benton2011EvaluatingGM,
  title={Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strains},
  author={Cristina S. Benton and Brooke H. Miller and Sean Skwerer and Oscar T Suzuki and Laura Schultz and Michael D. Cameron and J. s. Marron and Mathew T. Pletcher and Tim Wiltshire},
  booktitle={Psychopharmacology},
  year={2011}
}
Identification of biomarkers that establish diagnosis or treatment response is critical to the advancement of research and management of patients with depression. Our goal was to identify biomarkers that can potentially assess fluoxetine response and risk to poor treatment outcome. We measured behavior, gene expression, and the levels of 36 neurobiochemical analytes across a panel of genetically diverse mouse inbred lines after chronic treatment with water or fluoxetine. Glyoxylase 1 (GLO1) and… CONTINUE READING

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