Evaluating Estimation Techniques in Medical Imaging Without a Gold Standard: Experimental Validation.

@article{Hoppin2003EvaluatingET,
  title={Evaluating Estimation Techniques in Medical Imaging Without a Gold Standard: Experimental Validation.},
  author={John W. Hoppin and Matthew A. Kupinski and Donald K. Wilson and Todd E. Peterson and Benjamin M Gershman and George A Kastis and Eric W. Clarkson and Lars R. Furenlid and Harrison H. Barrett},
  journal={Proceedings of SPIE--the International Society for Optical Engineering},
  year={2003},
  volume={5034}
}
Imaging is often used for the purpose of estimating the value of some parameter of interest. For example, a cardiologist may measure the ejection fraction (EF) of the heart to quantify how much blood is being pumped out of the heart on each stroke. In clinical practice, however, it is difficult to evaluate an estimation method because the gold standard is not known, e.g., a cardiologist does not know the true EF of a patient. An estimation method is typically evaluated by plotting its results… CONTINUE READING

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