Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during development

@article{Okamoto2011EutherianMU,
  title={Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during development},
  author={Ikuhiro Okamoto and Catherine Patrat and Dominique Th{\'e}pot and Nathalie Peynot and Patricia Fauque and Nathalie Daniel and Patricia Diabangouaya and Jean-Philippe Wolf and Jean-Paul Renard and V{\'e}ronique Duranthon and Edith Heard},
  journal={Nature},
  year={2011},
  volume={472},
  pages={370-374}
}
X-chromosome inactivation (XCI) in female mammals allows dosage compensation for X-linked gene products between the sexes. The developmental regulation of this process has been extensively investigated in mice, where the X chromosome of paternal origin (Xp) is silenced during early embryogenesis owing to imprinted expression of the regulatory RNA, Xist (X-inactive specific transcript). Paternal XCI is reversed in the inner cell mass of the blastocyst and random XCI subsequently occurs in… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 186 CITATIONS, ESTIMATED 74% COVERAGE

Statistical Mechanics Models of Chromatin Architecture

VIEW 8 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

New Advances in Human X Chromosome Status from a Developmental and Stem Cell Biology

  • Tissue Engineering and Regenerative Medicine
  • 2017
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Regulation of X-chromosome dosage compensation in human: mechanisms and model systems.

  • Philosophical transactions of the Royal Society of London. Series B, Biological sciences
  • 2017
VIEW 11 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

Human Naive Pluripotent Stem Cells Model X Chromosome Dampening and X Inactivation.

  • Cell stem cell
  • 2016
VIEW 7 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2011
2019

CITATION STATISTICS

  • 32 Highly Influenced Citations

  • Averaged 20 Citations per year from 2017 through 2019

References

Publications referenced by this paper.
SHOWING 1-10 OF 42 REFERENCES

analysis of the gene regulative network controllingXist expression inmouse embryonic stem cells

P. Navarro, Avner, P. An embryonic story
  • Bioessays 32, 581–588
  • 2010

Dynamic changes in paternal X-chromosome activity during imprinted X-chromosome inactivation in mice

C Patrat
  • Proc. Natl Acad. Sci. USA 106,
  • 2009