European guidelines for quality assurance in cervical cancer screening: recommendations for clinical management of abnormal cervical cytology, part 1

@article{Jordan2008EuropeanGF,
  title={European guidelines for quality assurance in cervical cancer screening: recommendations for clinical management of abnormal cervical cytology, part 1},
  author={Joe Jordan and Marc Arbyn and Pierre Martin-Hirsch and U. Schenck and Jean Jacques Baldauf and Daniel Pereira da Silva and Ahti Anttila and Pekka Nieminen and Walter J Prendiville},
  journal={Cytopathology},
  year={2008},
  volume={19}
}
The current paper presents the first part of Chapter 6 of the second edition of the European Guidelines for Quality Assurance in Cervical Cancer Screening. It provides guidance on how to manage women with abnormal cervical cytology. Throughout this article the Bethesda system is used for cervical cytology terminology, as the European guidelines have recommended that all systems should at least be translated into that terminology while cervical intraepithelial neoplasia (CIN) is used for… Expand
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References

SHOWING 1-10 OF 102 REFERENCES
European guidelines for quality assurance in cervical cancer screening: recommendations for cervical cytology terminology
TLDR
The following short annexe to Chapter 3 of the European Guidelines for Quality Assurance in Cervical Cancer Screening provides a framework that will allow different terminologies and languages to be translated into standard terminology based on the Bethesda system for cytology while retaining the cervical intraepithelial neoplasia (CIN) classification for histology. Expand
Clinical utility of HPV-DNA detection: triage of minor cervical lesions, follow-up of women treated for high-grade CIN: an update of pooled evidence.
TLDR
HPV testing using the Hybrid Capture II test is more effective (more sensitive, equally specific) than cytology for the triage of patients with ASCUS Pap smears and for predicting recurrence of CIN in women treated for high-grade CIN. Expand
Interim Guidelines for Management of Abnormal Cervical Cytology
TLDR
In recent years it has become evident that the cost and morbidity associated with the detection and treatment of low-grade cervical lesions have escalated, probably increasing the likelihood of women developing cervical cancer. Expand
Comparison of Management Algorithms for the Evaluation of Women With Low‐Grade Cytologic Abnormalities
TLDR
A repeat Papanicolaou smear combined with a HPV DNA test is a sensitive alternative to colposcopic evaluation for the detection of CIN in women referred for a previous low-grade abnormal PAP smear, but because of the low specificity, it results in only modest cost reductions compared to the more standard triage of performing colposcopy at the first visit. Expand
Have we resolved how to triage equivocal cervical cytology?
TLDR
A metaanalysis comparing the performance of two triage strategies following an ASCUS result: repeating a cytology test and HPV DNA testing is reported, helpful in solidifying the understanding of HPVDNA testing and repeat cytology in the triage of equivocal Pap tests and in directing the course of future research. Expand
Chapter 9: Clinical applications of HPV testing: a summary of meta-analyses.
TLDR
Sufficient evidence exists to recommend HPV testing in triage of women with atypical cytology and in surveillance after treatment of CIN lesions, and the European screening policy will be reviewed based on the longitudinal results of randomised population trials which are currently underway. Expand
Virologic versus cytologic triage of women with equivocal Pap smears: a meta-analysis of the accuracy to detect high-grade intraepithelial neoplasia.
TLDR
The published literature indicates that the Hybrid Capture II assay has improved accuracy (higher sensitivity, similar specificity) than the repeat Pap smear using the threshold of ASCUS for an outcome of CIN2+ among women with equivocal cytologic results. Expand
The presence of persistent high‐risk hpv genotypes in dysplastic cervical lesions is associated with progressive disease: Natural history up to 36 months
TLDR
The results show that the continuous presence of high‐risk HPV types in women with cytomorphologically abnormal smears is a strong marker for progressive CIN disease. Expand
Comparison of three management strategies for patients with atypical squamous cells of undetermined significance: baseline results from a randomized trial.
TLDR
HC 2 testing for cancer-associated HPV DNA is a viable option in the management of women with ASCUS and has greater sensitivity to detect CIN3 or above and specificity comparable to a single additional cytologic test indicating ASCUS or above. Expand
Management of women who test positive for high-risk types of human papillomavirus: the HART study
TLDR
Comparison of the detection rate and positive predictive values of HPV assay with cytology and the best management strategy for HPV-positive women found HPV testing was more sensitive than borderline or worse cytology but less specific for detecting CIN2+. Expand
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