European Consensus Statement on Lung Cancer: Risk factors and prevention. Lung Cancer Panel

  title={European Consensus Statement on Lung Cancer: Risk factors and prevention. Lung Cancer Panel},
  author={Hans Konrad Biesalski and Bas Bueno De Mesquita and Andrew L. Chesson and Frank Chytil and Robert Francis Grimble and Rudolph J. J. Hermus and Jochen K{\"o}hrle and Reuben Lotan and Karl Norpoth and Ugo Pastorino and D I Thurnham},
  journal={CA: A Cancer Journal for Clinicians},
This article is based on discussions of the lung cancer panel at the Hohenheim Consensus Meeting organized by the World Health Organization and the German Ministry of Health in November 1996. Panel members were international experts in the field of diet and cancer who discussed specific questions relating to lung cancer risk factors and prevention. 

Commentary on “European Consensus Statement on Lung Cancer”

The “European Consensus Statement on Lung Cancer,” which appears in this issue1 (a slightly revised version of the paper originally published in the European Journal of Cancer Prevention), represents a reasonable synopsis of the current state-of-the-science of lung cancer risk factors and prevention but falls somewhat short of outlining where one could, and perhaps should, go from here.

Association between diabetes or antidiabetic therapy and lung cancer: A meta‐analysis

The quantitative estimates for the association between diabetes or antidiabetic treatment and lung cancer risk in the present meta‐analysis are provided.


Environmental risk factor like Cigarette or Beedi smoking, air pollution, presence of arsenic in Water and soil, radon gas, asbestos, use of insecticides or Pesticides, diesel exposure are linked to genesis of Lung Cancer.

American Cancer Society Guidelines on Nutrition and Physical Activity for Cancer Prevention: Reducing the Risk of Cancer with Healthy Food Choices and Physical Activity

The American Cancer Society (ACS) has set aggressive challenge goals for the nation to decrease cancer incidence and mortality—and to improve the quality of life of cancer survivors—by the year 2015.

Dietary factors and cancer risk.

  • N. Cotugna
  • Medicine, Political Science
    Seminars in oncology nursing
  • 2000
Evidence indicates that dietary factors can reduce the risk of developing cancer and the dietary recommendations for cancer risk reduction are consistent with those for prevention of other chronic diseases and are thus useful for the majority of the population.

Risk factors analysis for mortality among a cohort of lung cancer patients

Age more than 60, performance status ≥ 2 and stage III and IV were found as significant independent factors linked with raised mortality rate.

Metformin Use and Lung Cancer Risk in Diabetic Patients: A Systematic Review and Meta-Analysis

Metformin use was related to a lower lung cancer risk in diabetic patients compared to nonusers, but this result was retrieved from observational studies and the findings need more well-designed RCTs to confirm the association.

Diagnosis and Molecular Classification of Lung Cancer.

This chapter will review the main current basis of the pathological diagnosis and classification of lung cancer incorporating the histopathological and molecular dimensions of the disease.

Social determinants of lung cancer incidence in Canada: A 13-year prospective study.

An inverse risk between lung cancer incidence and educational attainment, income and occupation emerged among men and women, and a stepped negative gradient in RRs was evident for all SES variables and age groups.



Molecular genetics of lung cancer.

The integration of this knowledge with data from other fields, including epidemiology, toxicology, carcinogen metabolism, clinical genetics and clinical cancer therapy, promises advancements in lung cancer risk assessment, screening, prevention, prognostic assessment and therapy.

Nutrition and lung cancer.

  • M. Cattaruzza
  • Medicine
    Annali di igiene : medicina preventiva e di comunita
  • 1989

Smoking-attributable cancer mortality in 1991: is lung cancer now the leading cause of death among smokers in the United States?

It would also appear that lung cancer has now displaced coronary heart disease as the single leading cause of excess mortality among smokers in the United States.

Adjuvant treatment of stage I lung cancer with high-dose vitamin A.

Daily oral administration of high-dose vitamin A is effective in reducing the number of new primary tumors related to tobacco consumption and may improve the disease-free interval in patients curatively resected for stage I lung cancer.

Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinol Efficacy Trial.

Results based on the pre-specified analytic method are presented, details about risk factors for lung cancer, and analyses of subgroups and of factors that possibly influence response to the intervention are presented.

Chemoprevention strategies in lung carcinogenesis.

Results of chemoprevention trials in head and neck cancer have demonstrated effective inhibition of the development of second primary tumors with the synthetic retinoid 13-cis-retinoic acid; investigators are hopeful this will be repeated in patients with lung cancer.

Epidemiologic evidence for beta-carotene and cancer prevention.

Overall results are promising and several plausible cancer preventive mechanisms have been reported for beta-carotene, but the ongoing human intervention studies will provide more answers regarding cancer prevention by beta- carotene but may need long follow-ups to be conclusive.

The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers.

No reduction in the incidence of lung cancer among male smokers is found after five to eight years of dietary supplementation with alpha-tocopherol or beta carotene, and this trial raises the possibility that these supplements may actually have harmful as well as beneficial effects.

Determination of biomarkers for intermediate end points in chemoprevention trials.

The evidence supporting the concept of field cancerization is detailed, results of tests of the potentially useful biomarkers proliferating cell nuclear antigen and blood group antigen are presented, and microassay techniques are more readily applicable to small biopsy samples.

The EUROSCAN Study. EUROSCAN Steering Committee.

Patients with head and neck cancers are prone to develop multiple primary cancers (see further), probably because the mucosa of the upper air and food passages is being exposed to the same carcinogens.