Eurifoloids A-R, structurally diverse diterpenoids from Euphorbia neriifolia.

@article{Zhao2014EurifoloidsAS,
  title={Eurifoloids A-R, structurally diverse diterpenoids from Euphorbia neriifolia.},
  author={Jin-Xin Zhao and Cui-ping Liu and Wei-Yan Qi and Mei-Ling Han and Ying-Shan Han and Mark A. Wainberg and Jian-Min Yue},
  journal={Journal of natural products},
  year={2014},
  volume={77 10},
  pages={2224-33}
}
Eighteen new diterpenoids, named eurifoloids A-R (1-18), including ingenane (1 and 2), abietane (3-7), isopimarane (8-12), and ent-atisane (13-18) types, along with four known analogues were isolated from Euphorbia neriifolia. Eurifoloid M (13) represents a rare class of ent-atisane-type norditerpenoid. Eurifoloids E (5) and F (6) exhibited significant anti-HIV activities, with EC50 values of 3.58 ± 0.31 (SI = 8.6) and 7.40 ± 0.94 μM (SI = 10.3), respectively.