Eupatorium cannabinum L.

  title={Eupatorium cannabinum L.},
  author={Herman J. Woerdenbag},
  journal={Pharmaceutisch Weekblad},
A review onEupatorium cannabinum L. is given, including botany, history and constituents. The sesquiterpene lactones are discussed in more detail, covering their biosynthesis, isolation, analysis and biological activity. Special attention is paid to the cytotoxic and antitumour activities of the sesquiterpene lactones. 

New Gemacranolides from Eupatorium hualienense

The isolation of the new sesquiterpene lactones 1–5, named eupahualins A–E, along with the known heliangolide eupasimplicin B, showed significant activities against cell lines of human chronic myelogenous leukemia and human bone cancer.

Sesquiterpene lactones of Eupatorium cannabinum

To isolate the substances that had been detected, the comminuted raw material was extracted with a tenfold amount of chloroform, and then the solvent was evaporated off and the sesquiterpene lactones

Eupatozansins A – C, Sesquiterpene Lactones from Eupatorium chinense var. tozanense

Phytochemical investigation of Eupatorium chinense var. tozanense has resulted in the isolation of three new germacranolides, designated as eupatozansins A–C (1–3), along with five known compounds,

Pharmacological activity of an Eupatorium cannabinum L. extract

Pharmacological activity of Eupatorium cannabinum L. hydroalcoholic extract have been studied with the use of two in vitro assays - DPPH reduction spectrophotometric assay, and evaluation of

Analysis of the essential oil from the roots of Eupatorium cannabinum subsp. corsicum (L.) by GC, GC-MS and 13C-NMR.

The essential oil from the roots of this aromatic plant has been studied by GC, GC-MS and by 13C-NMR and was characterized by a high content of oxygenated compounds, particularly oxygenated monoterpenes.

Bioactive-guided Identification of Labdane Diterpenoids from Aerial Parts of Aristeguietia glutinosa as anti-Trypanosoma cruzi agents

Labdene 1, equipotent as the reference compound (Nifurtimox), displayed low hemolytic activity, low toxicity against murine macrophages, and absence of mutagenicity, which support the vernacular medicinal use of this plant as an anti-T.

Variability, toxicity, and antioxidant activity of Eupatorium cannabinum (hemp agrimony) essential oils

Investigation on pharmacological properties (antioxidant and toxic activities) of essential oils of E. cannabinum, collected from 11 wild populations in Lithuania, provided some new data concerning chemical composition and pharmaceutical properties of the plant.

Evaluation of Eupatorium cannabinum Linn. oil in enhancement of shelf life of mango fruits from fungal rotting

The essential oil of Eupatorium cannabinum was found to be fungitoxic in nature against both the mango-rotting fungi and was recorded to be more efficient than some synthetic fungicides.

The genus Eupatorium L. (Asteraceae): A review of their antimicrobial activity

The main phytochemical and biological characteristics of the Asteraceae family and the genus Eupatorium s.l., whose antimicrobial activity is promising, especially antibacterial and antifungal activity are presented.



Antitumor agents. II. Eupatolide, a new cytotoxic principle from Eupatorium formosanum HAY.

An alcoholic extract of the aboveground parts of Eupatorium formosanum, which showed significant inhibitory activity of the in vitro growth of tissue culture cells derived from human epidermoid

The Biogenesis and Chemistry of Sesquiterpene Lactones

It is the major goal of this review to present the presently known naturally occurring sesquiterpene lactones and their distribution in the plant kingdom. Furthermore, biogenetic hypotheses

Hiyodorilactones D,E, and F, new cytotoxic sesquiterpene lactones from Eupatorium sachalinense Makino.

Three new cytotoxic germacranolides, hiyodorilactones D, E, and F were isolated from the leaves of Eupatorium sachalinense MAKINO, and their structures were determined to be 4, 5, and 6,

Sesquiterpene lactones XVII. Cytostatic and pharmacological activity.

Of four lactones studied in the systems Sa-180, EAC and L-1210, two compounds: alatolide, (ALA) and eupatoriopicrin (EUPP), according to the criteria of CCNSC, showed high cytostatic activity, and

Structure-activity relationships among in vivo active germacranolides.

Nine structurally related germacranolides were assayed in two standard tumor systems and the moieties necessary for in vivo activity were found to be an alpha,beta-unsaturated ester side chain adjacent to the gamma-lactone and either a primary or secondary allylic alcohol or both.

Plant Mono-, Di- and Sesquiterpenoids with Pharmacological or Therapeutical Activity

The number of known mono-, di- and sesquiterpenoids has increased explosively in recent years. While the chemistry of certain monoterpenes and isoprene occupied some of the ablest chemists for many