Eupalinin A isolated from Eupatorium chinense L. induces autophagocytosis in human leukemia HL60 cells.

Abstract

Eupalinin A, a natural phytoalexin included in Eupatorium chinense L., exhibited a marked inhibitory effect on cell growth in HL60 cells. The morphological aspects of eupalinin A-treated cells evaluated by Hoechst 33342 nuclear staining indicated cell death, only a small part of which showed a typical apoptosis with nuclear fragmentation and condensation… (More)

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@article{Itoh2008EupalininAI, title={Eupalinin A isolated from Eupatorium chinense L. induces autophagocytosis in human leukemia HL60 cells.}, author={Tomohiro Itoh and Yuko Ito and Kenji Ohguchi and Masayoshi Ohyama and Munekazu Iinuma and Yoshinori Otsuki and Yoshinori Nozawa and Yukihiro Akao}, journal={Bioorganic & medicinal chemistry}, year={2008}, volume={16 2}, pages={721-31} }