Eukaryotic translation initiation factor 4E (eIF4E) expression is associated with breast cancer tumor phenotype and predicts survival after anthracycline chemotherapy treatment

@article{Heikkinen2013EukaryoticTI,
  title={Eukaryotic translation initiation factor 4E (eIF4E) expression is associated with breast cancer tumor phenotype and predicts survival after anthracycline chemotherapy treatment},
  author={Tuomas Heikkinen and Taina Korpela and Rainer Fagerholm and Sofia Khan and Kristiina Aittom{\"a}ki and P{\"a}ivi Heikkil{\"a} and Carl Blomqvist and Olli Carp{\'e}n and Heli Nevanlinna},
  journal={Breast Cancer Research and Treatment},
  year={2013},
  volume={141},
  pages={79-88}
}
Abnormal translation of mRNAs frequently occurring during carcinogenesis is among the mechanisms that can affect the expression of proteins involved in tumor development and progression. Eukaryotic initiation factor eIF4E is a key regulator of translation of many cancer-related transcripts and its expression is altered in various cancers and has been… CONTINUE READING