Eukaryotic genomes may exhibit up to 10 generic classes of gene promoters

@inproceedings{Gagniuc2012EukaryoticGM,
  title={Eukaryotic genomes may exhibit up to 10 generic classes of gene promoters},
  author={Paul A Gagniuc and Constantin Ionescu-T{\^i}rgovişte},
  booktitle={BMC Genomics},
  year={2012}
}
The main function of gene promoters appears to be the integration of different gene products in their biological pathways in order to maintain homeostasis. Generally, promoters have been classified in two major classes, namely TATA and CpG. Nevertheless, many genes using the same combinatorial formation of transcription factors have different gene expression patterns. Accordingly, we tried to ask ourselves some fundamental questions: Why certain genes have an overall predisposition for higher… CONTINUE READING
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Review Article The logic of chromatin architecture and remodelling at promoters

  • RC Bradley
  • Nature
  • 2009
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