Eukaryotic complex I: functional diversity and experimental systems to unravel the assembly process

@article{Remacle2008EukaryoticCI,
  title={Eukaryotic complex I: functional diversity and experimental systems to unravel the assembly process},
  author={Claire Remacle and M. Rosario Barbieri and Pierre Cardol and Patrice Paul Hamel},
  journal={Molecular Genetics and Genomics},
  year={2008},
  volume={280},
  pages={93-110}
}
With more than 40 subunits, one FMN co-factor and eight FeS clusters, complex I or NADH:ubiquinone oxidoreductase is the largest multimeric respiratory enzyme in the mitochondria. In this review, we focus on the diversity of eukaryotic complex I. We describe the additional activities that have been reported to be associated with mitochondrial complex I and discuss their physiological significance. The recent identification of complex I-like enzymes in the hydrogenosome, a mitochondria-derived… CONTINUE READING
28 Citations
196 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 28 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 196 references

Similar Papers

Loading similar papers…