Eukaryotic Translation Elongation is Modulated by Single Natural Nucleotide Derivatives in the Coding Sequences of mRNAs

@inproceedings{Hoernes2019EukaryoticTE,
  title={Eukaryotic Translation Elongation is Modulated by Single Natural Nucleotide Derivatives in the Coding Sequences of mRNAs},
  author={Thomas Philipp Hoernes and David Heimd{\"o}rfer and Daniel Koestner and Klaus Faserl and Felix Nu{\ss}baumer and Raphael Plangger and Christoph Kreutz and Herbert Lindner and Matthias David Erlacher},
  booktitle={Genes},
  year={2019}
}
RNA modifications are crucial factors for efficient protein synthesis. All classes of RNAs that are involved in translation are modified to different extents. Recently, mRNA modifications and their impact on gene regulation became a focus of interest because they can exert a variety of effects on the fate of mRNAs. mRNA modifications within coding sequences can either directly or indirectly interfere with protein synthesis. In order to investigate the roles of various natural occurring modified… CONTINUE READING
1
Twitter Mention

Similar Papers

References

Publications referenced by this paper.
SHOWING 1-10 OF 70 REFERENCES

2′-O-methylation in mRNA disrupts tRNA decoding during translation elongation

  • Nature Structural & Molecular Biology
  • 2018
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL