Eukaryotic Intron Loss

  title={Eukaryotic Intron Loss},
  author={Tobias Mourier and Daniel C. Jeffares},
  pages={1393 - 1393}
Recently, attention has been drawn to eukaryotic genomes with very few introns ( [1][1], [2][2] ) and to the biased position of introns within genes ( [3][3] ). We show here that intron-poor eukaryotes for which genome data is available have a 5′ bias in the position of their introns within genes 
Intron-rich ancestors.
  • S. Roy
  • Biology
    Trends in genetics : TIG
  • 2006
Intron Loss and Gain
Variation in intron abundance in eukaryotic genomes signifies that intron loss and intron gain have occurred at varying degrees during the evolution of eUKaryotes.
The biology of intron gain and loss.
Progress in Eukaryotic Intron *
Some progress is reviewed in intron distrubtion, intron generated hypothesis, spliceosome and major splice sites, introns acquisition and lose and its mechanisms, factors affecting the evolution of intron, and so on.
The intronome of budding yeasts.
The rise and falls of introns
The absence of introns that are not self-splicing in prokaryotes and several other lines of evidence suggest an ancient eukaryotic origin for these introns, and the subsequent gain and loss of intrusion appears to be an ongoing process in many organisms.
Intron-dominated genomes of early ancestors of eukaryotes.
It is suggested that early ancestral eukaryotic genomes consisted of up to 80% sequences derived from Group II introns, a much greater contribution of introns than that seen in any extant genome.
The excess of 5′ introns in eukaryotic genomes
The most parsimonious explanation for the findings may be the model in which intron loss is caused by homologous recombination between the genomic copy of a gene and a reverse transcriptase product of a spliced mRNA.


The ins and outs of group II introns.
Eukaryotic evolution: Early origin of canonical introns
Intons from a close relative of Giardia, Carpediemonas membranifera, are described that have boundary sequences of the normal eukaryotic type, indicating that canonical introns are likely to have arisen very early in eukARYotic evolution.
A spliceosomal intron in Giardia lamblia
Phylogenetic analyses show the Giardia Sm core peptides are the products of multiple, ancestral gene duplications followed by divergence, but they retain strong similarity to Sm and like-Sm peptides of other eukaryotes.
Pseudogenes in yeast?
De novo synthesis of an intron by the maize transposable element Dissociation.
Alternative RNA splicing patterns that result in precise removal of a Dissociation (Ds) insertion and one copy of its eight-nucleotide host site duplication from an exon sequence of the maize shrunken2-mutabe1 (sh2-m1) mutant are described.
Sequence of Plasmodium falciparum chromosomes 1, 3–9 and 13
The sequence of chromosomes 1, 3–9 and 13 of P. falciparum clone 3D7 is reported—these chromosomes account for approximately 55% of the total genome, and a highly conserved sequence element is identified in the intergenic region of internal var genes that is not associated with their telomeric counterparts.
Human LINE retrotransposons generate processed pseudogenes
It is shown–by introducing deletions within either coding sequence of the human LINE–that both ORFs are necessary for the formation of the processed pseudogenes, and that retroviral-like elements are not able to produce similar structures in the same assay, strengthening the unique versatility of LINEs as genome modellers.
Archaea and the prokaryote-to-eukaryote transition.
This review considers the cumulative knowledge about the Archaea in relationship to the Bacteria and Eucarya and the recent use of molecular phylogenetic approaches to reconstructing the tree of life.
The human genome browser at UCSC.
A mature web tool for rapid and reliable display of any requested portion of the genome at any scale, together with several dozen aligned annotation tracks, is provided at