Eukaryotic GCP1 is a conserved mitochondrial protein required for progression of embryo development beyond the globular stage in Arabidopsis thaliana.

@article{Haussuehl2009EukaryoticGI,
  title={Eukaryotic GCP1 is a conserved mitochondrial protein required for progression of embryo development beyond the globular stage in Arabidopsis thaliana.},
  author={Kirsten Haussuehl and Pitter F. Huesgen and Marc E. Meier and Patrick Dessi and Elzbieta Glaser and Jerzy Adamski and Iwona Adamska},
  journal={The Biochemical journal},
  year={2009},
  volume={423 3},
  pages={333-41}
}
GCPs (glycoproteases) are members of the HSP70 (heat-shock protein 70)/actin ATPase superfamily that are highly conserved in taxonomically diverse species from bacteria to man, suggesting an essential physiological role. Although originally identified and annotated as putative endopeptidases, a proteolytic activity could not be confirmed for these proteins. Our survey of genome databases revealed that all eukaryotic organisms contain two GCP genes [called GCP1 and GCP2/Kae1 (kinase-associated… CONTINUE READING
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