Eukaryote evolution: Engulfed by speculation

  title={Eukaryote evolution: Engulfed by speculation},
  author={Anthony M. Poole and David Penny},
The notion that eukaryotes evolved via a merger of cells from the other two domains — archaea and bacteria — overlooks known processes. It is generally agreed that the mitochondrion, powerhouse of the eukaryote cell, evolved from an engulfed bacterium. But what did the engulfing? Did an archaeon engulf a bacterium? Did an RNA cell engulf an archaeon and a mitochondrial ancestor? The permutations are seemingly endless. Anthony Poole and David Penny argue that in this field, speculation has run… 

Predation between prokaryotes and the origin of eukaryotes

According to the model presented here, the eukaryotic cell originated from a merger of two prokaryotes, an archaeal host and a bacterial endosymbiont, which penetrated and replicated within the host periplasm, and later became the mitochondria.

Domain Cell Theory supports the independent evolution of the Eukarya, Bacteria and Archaea and the Nuclear Compartment Commonality hypothesis

How simple the NuCom hypothesis is in explaining eukaryote evolution relative to the other hypotheses is discussed and the philosophical importance of simplicity and its relationship to truth in hypotheses such as NuCom and Domain Cell Theory is presented.

The origin of eukaryotes and their relationship with the Archaea: are we at a phylogenomic impasse?

The origin of eukaryotes and their evolutionary relationship with the Archaea is a major biological question and the subject of intense debate, with several recent large-scale phylogenomic studies divided in supporting either one or the other scenario, despite analysing largely overlapping data sets of universal genes.

Eukaryotic origins: How and when was the mitochondrion acquired?

It is shown here that the associations between specific cell biological models of eukaryogenesis and evolutionary genomic data are not as strong as many suppose.

Origin of eukaryotes from within archaea, archaeal eukaryome and bursts of gene gain: eukaryogenesis just made easier?

  • E. Koonin
  • Biology
    Philosophical Transactions of the Royal Society B: Biological Sciences
  • 2015
Comparative genomic analysis clearly shows that the last eukaryotic common ancestor (LECA) possessed most of the signature complex features of modern eUKaryotic cells, in particular the mitochondria, the endomembrane system including the nucleus, an advanced cytoskeleton and the ubiquitin network.

Archaeal ancestors of eukaryotes: not so elusive any more

The latest striking discovery made by deep metagenomic sequencing vindicates the hypothesis that in phylogenetic trees eukaryotes fall within a newly identified archaeal group, the Lokiarchaeota, which combine several eukARYotic signatures previously identified in different archaea.

Critique of the latest evolutionary models of the beginning of life

Poor resolution of the tree of life containing Eukarya and Archaea indicates that the supposed evolutionary origin of these groups is not clear-cut, and that instead they A number of recent evolutionary models are considered and reviewed.

Breaking through a phylogenetic impasse: a pair of associated archaea might have played host in the endosymbiotic origin of eukaryotes

Evidence is presented that not just one, but a pair of archaea might have served as host to the bacterial ancestor of the mitochondria, which may have consisted of ancestors of both Ignicoccus hospitalis as well as its ectosymbiont/ectoparasite ‘Nanoarchaeum equitans’.

Energetics and genetics across the prokaryote-eukaryote divide

The combination of massive bioenergetic expansion, release from genome-size constraints, and high mutation rate explained the unique origin of eukaryotes, the absence of true evolutionary intermediates, and the evolution of sex in eukaries but not prokaryotes.