Eukarya the chimera: eukaryotes, a secondary innovation of the two domains of life?

  title={Eukarya the chimera: eukaryotes, a secondary innovation of the two domains of life?},
  author={Stephanie-Jane Nobs and Fraser Macleod and Hon Lun Wong and Brendan Paul Burns},
  journal={Trends in Microbiology},



Cell division in the archaeon Haloferax volcanii relies on two FtsZ proteins with distinct functions in division ring assembly and constriction.

It is shown that Haloferax volcanii cannot divide properly without either or both FtsZ proteins, but DNA replication continues and cells proliferate in alternative ways, such as blebbing and fragmentation, via remarkable envelope plasticity.

Complex Evolution of the Mismatch Repair System in Eukaryotes is Illuminated by Novel Archaeal Genomes

This new analysis provided evidence for a complex evolutionary history of eukaryotic MMR: an archaeal origin for the nuclear MMR system in eUKaryotes, with subsequent acquisitions of other MMR systems from organelles.

Mythical origins of the actin cytoskeleton.

Insights into the evolution of regulated actin dynamics via characterization of primitive gelsolin/cofilin proteins from Asgard archaea

Actin filament severing, capping, annealing and bundling, and monomer sequestration activities by gelsolin proteins from Thorarchaeota (Thor), which complete a eukaryotic-like actin depolymerization cycle, and indicate complex actin cytoskeleton regulation in Asgard organisms.

Microbial dark matter filling the niche in hypersaline microbial mats

This is the first study to reconstruct and describe in detail metagenome-assembled genomes (MAGs) affiliated with microbial dark matter in hypersaline microbial mats, suggesting that these microbial groups are major players in these systems.

Coevolution of Eukaryote-like Vps4 and ESCRT-III Subunits in the Asgard Archaea

Evidence is provided that the ESCRT complexes from Asgard archaea and eukaryotes are evolutionarily related and functionally similar, suggesting that despite the apparent absence of endomembranes in archaea, Eukaryotic ESCRT was inherited from an Asgard archaeal ancestor, alongside the emergence of endOMembrane system during eUKaryogenesis.

The Syntrophy hypothesis for the origin of eukaryotes revisited

The Syntrophy hypothesis for the origin of eukaryotes is updated, considering recent advances in the archaeal field about the physiology, metabolism, ecology and evolution of these microbes, and several model predictions are discussed and how these can be tested.

Timing the origin of eukaryotic cellular complexity with ancient duplications

This scenario bridges the signs of complexity observed in Asgard archaeal genomes to the proposed role of mitochondria in triggering eukaryogenesis, and shows that the Asgard archaea-related host already had some eUKaryote-like cellular complexity, which increased further upon mitochondrial acquisition.