Etravirine concentrations in CSF in HIV-infected patients.

@article{Tiraboschi2012EtravirineCI,
  title={Etravirine concentrations in CSF in HIV-infected patients.},
  author={Juan Manuel Tiraboschi and Jordi Niub{\'o} and Antonia Teresah Vila and S{\'i}lvia P{\'e}rez-Pujol and Daniel Podzamczer},
  journal={The Journal of antimicrobial chemotherapy},
  year={2012},
  volume={67 6},
  pages={1446-8}
}
OBJECTIVES To determine etravirine concentrations in CSF in HIV-infected patients. METHODS Twelve HIV-1 adult antiretroviral-experienced patients receiving an etravirine-containing regimen for at least 1 month were enrolled. Both CSF and blood samples were taken around 12 h after the last etravirine dose. Liquid chromatography-tandem mass spectrometry was used to determine etravirine concentrations, and HIV-1 viral load was determined by real-time PCR (limit of detection 40 copies/mL… CONTINUE READING