Etodolac Clinical Pharmacokinetics

@article{Brocks1994EtodolacCP,
  title={Etodolac Clinical Pharmacokinetics},
  author={D. Brocks and F. Jamali},
  journal={Clinical Pharmacokinetics},
  year={1994},
  volume={26},
  pages={259-274}
}
  • D. Brocks, F. Jamali
  • Published 1994
  • Medicine
  • Clinical Pharmacokinetics
  • SummaryEtodolac is a chiral nonsteroidal anti-inflammatory drug (NSAID) that is marketed as the racemate. Currently, the drug is available in several countries for the treatment of arthritis and the alleviation of pain.Etodolac possesses several unique disposition features mainly due to its stereoselective pharmacokinetics. In plasma, the concentrations of the ‘inactive’ R-enantiomer are about 10-fold higher than those of the active S-enantiomer, an observation that is novel among the chiral… CONTINUE READING
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