Etiopathogenesis of Behçet's disease with emphasison the role of immunological aberrations

  title={Etiopathogenesis of Behçet's disease with emphasison the role of immunological aberrations},
  author={Violetta D. Kapsimali and Meletios A Kanakis and George A. Vaiopoulos and Phaedon G. Kaklamanis},
  journal={Clinical Rheumatology},
Behçet's disease (BD) is a chronic multisystemic inflammatory disorder of unknown origin consisting of oral aphthous ulcers, ocular symptoms, skin lesions, and genital ulcerations. It has many features in common with systemic vasculitides and is more prevalent in countries along the ancient Silk route. Immune-mediated mechanisms play a major role in the pathogenesis of the disease, and inflammatory mediators are also involved. BD is not considered to be an autoimmune disorder, and the character… CONTINUE READING
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