Etiology of first‐ever ischaemic stroke in European young adults: the 15 cities young stroke study

  title={Etiology of first‐ever ischaemic stroke in European young adults: the 15 cities young stroke study},
  author={N Yesilot Barlas and Jukka Putaala and Ulrike Waje-Andreassen and Sophia Vassilopoulou and Katiuscia Nardi and C{\'e}line Odier and Gergely Hofg{\'a}rt and S. Engelter and Annika Burow and L{\'a}szl{\'o} Mih{\'a}lka and Manja Kloss and Julia Ferrari and Robin Lemmens and Oğuzhan Çoban and Elena Haapaniemi and Noortje A M M Maaijwee and Loes C A Rutten-Jacobs and Anna Bersano and Carlo W. Cereda and Pierluigi Baron and Linda Borellini and Caterina Valcarenghi and Lars Thomassen and Armin J. Grau and Frederick Palm and Christian Urbanek and Rezzan Tunçay and A Durukan Tolvanen and Ewoud J. van Dijk and F.‐E. Leeuw and Vincent N. Thijs and Stefan Greisenegger and Konstantinos N. Vemmos and C. Lichy and D{\'a}niel Bereczki and L{\'a}szl{\'o} Csiba and Patrik Michel and Didier Leys and Konstantinos M Spengos and Halvor Naess and Turgut Tatlisumak and Sara Zarko Bahar},
  journal={European Journal of Neurology},
Risk factors for IS in young adults differ between genders and evolve with age, but data on the age‐ and gender‐specific differences by stroke etiology are scare. These features were compared based on individual patient data from 15 European stroke centers. 

Age dependency of ischaemic stroke subtypes and vascular risk factors in western Norway: the Bergen Norwegian Stroke Cooperation Study

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Mortality in young adult patients with acute ischaemic stroke

This study aimed to determine short‐ and long‐term mortality, clinical determinants and causes of death in young patients with ischaemic stroke.

Embolic strokes of undetermined source in young adults: baseline characteristics and long‐term outcome

The clinical characteristics and long‐term risks of vascular events and all‐cause mortality between young‐onset ESUS and other aetiological subgroups were compared.

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There is no universally accepted age cut‐off for defining young strokes, so strokes up to the age of 18 may be considered to be young.

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“Young Stroke” Risks Potentially Linked to the Flammer Syndrome Phenotype: Facts and Hypotheses

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Evaluated the prevalence of non‐obstructive carotid atherosclerosis (NOCA) and its association with patent foramen ovale (PFO) in young adults with cryptogenic stroke (CS).

Cerebrovascular Risk Profiles in a Saudi Arabian Cohort of Young Stroke Patients

Cerebrovascular risk profiles and stroke etiologies in a Saudi Arabic cohort of consecutive young stroke patients differ from those of previous cohorts, suggesting the need for tailored prevention strategies that take into account local epidemiological data on cerebrov vascular health.

Characteristics and Outcomes of Young Patients with First-Ever Ischemic Stroke Compared to Older Patients: The National Acute Stroke ISraeli Registry

The findings of this nationwide registry demonstrate the relatively high rate of smoking and family history of stroke, and the lower rate of hospital arrival by ambulance among young adults, and calls for increasing awareness to the possibility of stroke amongYoung adults and for better prevention, especially smoking cessation.

Strokes in young adults: epidemiology and prevention

  • D. Smajlović
  • Medicine, Psychology
    Vascular health and risk management
  • 2015
Strokes in young adults are a major public health problem and further research, with standardized methodology, is needed in order to give us more precise epidemiologic data.



Risk factors, etiology, and outcome of first‐ever ischemic stroke in young adults aged 15 to 45 – the Athens young stroke registry

Evaluation of risk factors, etiology, and outcome in a hospital‐based prospective observational study in young adults from Greece aimed to evaluate risk factors and etiology.

Distribution of etiologies in patients above and below age 45 with first‐ever ischemic stroke

This work has shown clear trends in the distribution of etiologies of ischemic stroke in different age groups, and these trends are likely to be related to age and disease progression.

Stroke in Young Women

  • M. SalisburyG. PfefferS. Yip
  • Medicine, Psychology
    Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
  • 2011
In women ages 15-45 years, an additional set of risk factors are important in the pathogenesis of ischemic stroke. Some of these pertain strictly to women, and relate to exogenous hormones and

Stroke in Young Adults in the Community-Based L’Aquila Registry: Incidence and Prognosis

Stroke patients <45 years of age showed a disproportionate cumulative high prevalence of subarachnoid and intracerebral hemorrhage with respect to older patients, mainly due to aneurysms and arteriovenous malformations, and screening procedures and preventive strategies in the young should also be addressed.

Analysis of 1008 Consecutive Patients Aged 15 to 49 With First-Ever Ischemic Stroke: The Helsinki Young Stroke Registry

The frequency of ischemic stroke increases sharply at age 40, and Etiology and risk factors start resembling those seen in the elderly in early midlife but causes defined in younger patients still are frequent in those aged 45 to 49.

Causes of ischemic stroke in young adults in Thailand: a pilot study.

Guidelines for management of ischaemic stroke and transient ischaemic attack 2008.

The article covers referral and emergency management, Stroke Unit service, diagnostics, primary and secondary prevention, general stroke treatment, specific treatment including acute management, management of complications, and rehabilitation.

Demographic and Geographic Vascular Risk Factor Differences in European Young Adults With Ischemic Stroke: The 15 Cities Young Stroke Study

Primary preventive strategies for ischemic stroke in young adults—having high rate of modifiable risk factors—should be targeted according to sex and age at continental level.

Differences in Vascular Risk Factors Between Etiological Subtypes of Ischemic Stroke: Importance of Population-Based Studies

Prevalences of risk factors and stroke subtype differ between hospitalized and nonhospitalized patients with ischemic stroke, which may bias hospital-based risk factor studies, and meta-analysis of population-based studies suggests that vascular risk factors differ between stroke subtypes.

Ischemic stroke in Korean young adults

Heavy exposure to risk factors such as hypertension and cigarette smoking in Korean young men may explain the differences in the characteristics of ischemic stroke.