Etiology of exercise-induced asthma: physical stress-induced transcription.

  title={Etiology of exercise-induced asthma: physical stress-induced transcription.},
  author={Thomas Hilberg},
  journal={Current allergy and asthma reports},
  volume={7 1},
Exercise-induced asthma (EIA) occurs with a high prevalence in both asthmatic and nonasthmatic individuals. Although understanding of the functional genomics (proteomics) in sports medicine remains limited, this review focuses on immunologic changes as reflected in transcriptional regulation in respect to EIA. Studies demonstrated that leukotrienes play a significant role in EIA. Exercise increases the distribution of leukotrienes and influences the leukotriene transcription pathway; it could… CONTINUE READING