Etiologies of epilepsy: a comprehensive review

  title={Etiologies of epilepsy: a comprehensive review},
  author={Devender Bhalla and Bertrand Godet and Michel Druet‐Cabanac and Pierre-Marie Preux},
  journal={Expert Review of Neurotherapeutics},
  pages={861 - 876}
Epilepsy is a heterogeneous disorder, the symptoms of which are preventable and controllable to some extent. Significant inter- and intra-country differences in incidence and prevalence exist because multiple etiologic factors are implicated. Many past reviews have addressed sole etiologies. We considered a comprehensive view of all etiologies (genetic/structural/metabolic) to be significant for both the developing and the developed world as well as routine clinical/epidemiology practice. We… 
Epidemiology of febrile seizures and epilepsy: a call for action.
Epilepsy in poor regions of the world
Characteristics and Features of Electroencephalography (EEG) in Children with Epilepsy
Conclution that pediatric epileptic patients present with a generalized type of epilepsy onset tonic-clonic motor with an unknown etiology.
The Causes of Secondary Epilepsy in Epileptic Patients Referred to Neurology Clinics of Mashhad Hospitals
This study showed that the average age of patients with previous history of stroke was higher than that of other participants, however, previous historyof stroke and head trauma mostly observed in males.
Predictors of Seizure Freedom in Patients Undergoing Surgery for Central Nervous System Infection-Related Epilepsy: A Systematic Review and Meta-Analysis
This meta-analysis suggests that abnormal MRI findings, meningitis, temporal location only, regional and unilateral ictal patterns, older age at epilepsy, longer silent period, and longer time from infection are predictive factors in patients with favorable surgical outcomes in CNSI-related epilepsy.
DITORIAL pidemiology of febrile seizures and epilepsy : a call or action
A population-based cross-sectional study conducted in the ity of Barra do Bugres in Brazil to assess the prevalence of febrile seizures during childhood finds the main outcome as a prevalence of 6.4/1000 habitants, which is much lower than the results in two studies also performed in Brazil.
Mortality in epilepsy and the influence of comorbid conditions and antiepileptic drugs
Treatment with LTG in females was significantly associated with SUDEP, and it remains uncertain whether a causal relationship is present, butComorbid and underlying disorders were the main determinants of mortality in the epilepsy population.


Epilepsy: an autoimmune disease?
  • J. Palace, B. Lang
  • Medicine, Psychology
    Journal of neurology, neurosurgery, and psychiatry
  • 2000
There is growing evidence that autoimmune mechanisms might have a role in some patients with Rasmussen's encephalitis, and numerous reports of the detection of theoretically relevant serum autoantibodies, experimental data showing that antibodies can be epileptogenic, and a response of some epilepsy syndromes to immunomodulation.
Genetic Aspects of Epilepsy
  • T. Tsuboi
  • Psychology, Medicine
    Folia psychiatrica et neurologica japonica
  • 1980
The author has reviewed the pertinent articles and indicated the present problems in the genetics of epilepsies, both clinical and genetical.
[Genetic aspects of epilepsy].
Etiologic factors and clinical features of symptomatic epilepsy: Focus on pediatric cases
Electroclinical characteristics of severe myoclonic epilepsy in infancy, the most intractable epilepsy syndrome in infancy is the focus and recent advances of genetic research are introduced.
Clinical characteristics in focal cortical dysplasia: a retrospective evaluation in a series of 120 patients.
Different age at epilepsy onset and transient responsiveness to antiepileptic drugs in approximately 17% of patients may reflect different dynamics in epileptogenicity of the underlying FCD.
[Multiple sclerosis and epileptic seizures].
The clinical, electroencephalographical and neuroimaging findings of seven patients with multiple sclerosis who had epileptic seizures and those in whom there was no evidence of other potentially epileptogenic pathology are reported.
Cerebral malaria and epilepsy
Recent African studies that examine the association between cerebral malaria and epilepsy suggest a modestly strong association, and there appears little doubt that this association is causal.
[Neonatal epilepsy and inborn errors of metabolism].
Clinicians are helping clinicians in reviewing potential metabolic diagnoses and approaching metabolic evaluations by identifying specific types of seizures that may suggest a specific metabolic disease.