Etiologic considerations of fulminant non-A, non-B viral hepatitis in Japan: analyses by nucleic acid amplification method.

@article{Fukai1998EtiologicCO,
  title={Etiologic considerations of fulminant non-A, non-B viral hepatitis in Japan: analyses by nucleic acid amplification method.},
  author={Kenichi Fukai and Osamu Yokosuka and Kenji Fujiwara and Masami Tagawa and Fumio Imazeki and Hiromitsu Saisho and Masao Omata},
  journal={The Journal of infectious diseases},
  year={1998},
  volume={178 2},
  pages={
          325-33
        }
}
The etiology of fulminant non-A, non-B hepatitis has remained unclear, even after the identification of hepatitis C and E viruses. To study the possible involvement of hepatitis B, C, D, and E virus infections, viral genomes were amplified by a sensitive polymerase chain reaction method in sera and liver tissues obtained from 20 patients serologically diagnosed with non-A, non-B fulminant hepatitis (n = 14), acute hepatitis severe type (n = 2), and ordinary acute hepatitis (n = 4). Hepatitis C… 
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Methods Citations
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20 Citations

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Sequence analysis of hepatitis C virus isolated from a fulminant hepatitis patient *
TLDR
HCV was isolated from a fulminant hepatitis patient and its entire genome was recovered; a clustering around genotype 2a was observed, but the sequence deviated especially in 5′UTR, core, NS3, and NS5A; and monoclonality of the HVR sequence was found not only in the fulminants hepatitis patient but in a certain percentage of chronic hepatitis patients.
Detection of Hepatitis B and G Virus Genomes in Sera from Patients with Acute Non-A, Non-B, Non-C Hepatitis (Orinigal)
TLDR
The results suggest that HBV is a cause of non-Anon-Bnon-C hepatitis.
Hepatitis B infection in patients with acute liver failure in the United States
TLDR
HBV precore and/or core promoter variants were common among US patients with ALF caused by hepatitis B, and occult HBV infection was not present in this large series of ALF patients in the United States.
The role of TT virus infection in acute viral hepatitis
TLDR
Although TTV was detected frequently in non–A‐A‐E acute hepatitis, no etiologic role for TTV could be established and the clinical characteristics of the acute illnesses were similar for patients with or without TTV in hepatitis non– A‐E, A, B, or C.
Clinical epidemiology of fulminant hepatitis in Japan before the substantial introduction of liver transplantation: an analysis of 1309 cases in a 15-year national survey.
Molecular epidemiology of hepatitis B, C, D and E viruses among children in Moscow, Russia.
  • K. Abe, E. Hayakawa, +5 authors V. Uchaikin
  • Medicine, Biology
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
  • 2004
Fulminant hepatic failure in a pediatric patient with active GB virus C (GBV-C)/hepatitis G virus (HGV) infection.
Prevalence of hepatitis virus types B through E and genotypic distribution of HBV and HCV in Ho Chi Minh City, Vietnam.
  • H. Tran, H. Ushijima, +6 authors K. Abe
  • Medicine, Biology
    Hepatology research : the official journal of the Japan Society of Hepatology
  • 2003
Small-bowel hemorrhage caused by cytomegalovirus vasculitis following fulminant hepatitis
TLDR
It is concluded that the possibility of CMV enteritis should be considered when patients present with unexplained fever and gastrointestinal hemorrhage following fulminant hepatitis, and the early administration of ganciclovir should be considering.
Etiopathogenesis of acute hepatic failure: Eastern versus Western countries
Abstract  Etiopathogenesis of acute hepatic failure (AHF) in Eastern and Western countries is distinct. In the East hepatitis viruses cause AHF in more than 95% of such cases, while causes of AHF in…
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