Etidronate versus fluoride for treatment of osteopenia in primary biliary cirrhosis: preliminary results after 2 years.

@article{Guaabens1997EtidronateVF,
  title={Etidronate versus fluoride for treatment of osteopenia in primary biliary cirrhosis: preliminary results after 2 years.},
  author={N{\'u}ria Gua{\~n}abens and Albert Pares and Ana Monegal and Pilar Peris and Françesca Pons and L San Emeterio Alvarez and Mar{\'i}a Jes{\'u}s Mart{\'i}nez de Osaba and Merc{\`e} Roca and Merc{\'e} Torra and J. J. Rodes},
  journal={Gastroenterology},
  year={1997},
  volume={113 1},
  pages={219-24}
}
BACKGROUND & AIMS Because osteopenia increases morbidity of primary biliary cirrhosis (PBC), the effects of cyclical etidronate vs. sodium fluoride on bone mass were compared in patients with PBC. METHODS Thirty-two women with PBC were randomly assigned to receive etidronate (400 mg/day during 14 days every 3 months) or fluoride (50 mg/day, enteric-coated tablets). Bone mineral density of the lumbar spine and proximal femur were measured initially and every 6 months. Bone fractures were also… CONTINUE READING
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