Ethyl pyruvate reduces mortality in an endotoxin-induced severe acute lung injury mouse model

Abstract

BACKGROUND Ethyl pyruvate (EP) was recently identified as an experimental therapeutic agent in a wide variety of model systems for inflammation-mediated tissue and cellular injury. OBJECTIVE To evaluate the effect of ethyl EP on improving the survival in mice with LPS-induced acute lung injury (ALI). METHODS ALI was induced by administering… (More)
DOI: 10.1186/1465-9921-10-91

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