Ethoxyresorufin-O-deethylase (EROD) activity in fish as a biomarker of chemical exposure.

@article{Whyte2000EthoxyresorufinOdeethylaseA,
  title={Ethoxyresorufin-O-deethylase (EROD) activity in fish as a biomarker of chemical exposure.},
  author={Jeffrey J. Whyte and Robin E. Jung and Christopher J Schmitt and Donald E. Tillitt},
  journal={Critical reviews in toxicology},
  year={2000},
  volume={30 4},
  pages={
          347-570
        }
}
This review compiles and evaluates existing scientific information on the use, limitations, and procedural considerations for EROD activity (a catalytic measurement of cytochrome P4501A induction) as a biomarker in fish. A multitude of chemicals induce EROD activity in a variety of fish species, the most potent inducers being structural analogs of 2,3,7,8-tetracholordibenzo-p-dioxin. Although certain chemicals may inhibit EROD induction/activity, this interference is generally not a drawback to… CONTINUE READING
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