Ethoxylated alcohol (Neodol-12) and other surfactants in the assay of protein kinase C.
@article{Abidi1989EthoxylatedA, title={Ethoxylated alcohol (Neodol-12) and other surfactants in the assay of protein kinase C.}, author={T. F. Abidi and C. A. Faaland and D. D. Scala and L. D. Rhein and J. Laskin}, journal={Biochimica et biophysica acta}, year={1989}, volume={992 3}, pages={ 362-8 } }
Most commonly used surfactants were found to be inhibitors of partially purified rat brain protein kinase C at or above their critical micellar concentrations (CMC). These include sodium lauryl sulfate, deoxycholate, octyl glucoside, dodecyl trimethylammonium bromide, linear alkylbenzene sulfonate and Triton X-100. Several detergents, including the nonionic surfactants digitonin and Neodol-12 (ethoxylated alcohol), did not inhibit protein kinase C activity, even at concentrations greater than… CONTINUE READING
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