Ethopharmacological analysis of rat behavior on the elevated plus-maze.

  title={Ethopharmacological analysis of rat behavior on the elevated plus-maze.},
  author={Ariane Pinheiro Cruz and Frances X. Frei and Frederico Guilherme Graeff},
  journal={Pharmacology, biochemistry, and behavior},
  volume={49 1},
Behavioral categories were measured in rats left on an elevated plus-maze for 5 min, in addition to the traditional measures. Four independent factors emerged from a factor analysis. The variables that loaded highly and positively on Factor 1, seemingly related with anxiety, were: number of entries onto open arms, time spent on open arms, percentage of open/total arm entries, percentage of time on open arms, scanning over the edge of an open arm, and open arm end-exploring. The time spent on… CONTINUE READING
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