Ethological concepts enhance the translational value of animal models.

  title={Ethological concepts enhance the translational value of animal models.},
  author={Suzanne M Peters and Helen H J Pothuizen and Berry M. Spruijt},
  journal={European journal of pharmacology},
The translational value of animal models is an issue of ongoing discussion. We argue that 'Refinement' of animal experiments is needed and this can be achieved by exploiting an ethological approach when setting up and conducting experiments. Ethology aims to assess the functional meaning of behavioral changes, due to experimental manipulation or treatment, in animal models. Although the use of ethological concepts is particularly important for studies involving the measurement of animal… CONTINUE READING
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