Ethiopia: between Sub‐Saharan Africa and Western Eurasia

@article{Lovell2005EthiopiaBS,
  title={Ethiopia: between Sub‐Saharan Africa and Western Eurasia},
  author={Alan D Lovell and Claudia Moreau and Vania Yotova and F. X. Xiao and Stephane Bourgeois and Dominik Gehl and Jaume Bertranpetit and Erwin Schurr and Damian Labuda},
  journal={Annals of Human Genetics},
  year={2005},
  volume={69}
}
Ethiopia is central to population genetic studies investigating the out of Africa expansion of modern humans, as shown by Y chromosome and mtDNA studies. To address the level of genetic differentiation within Ethiopia, and its relationship to Sub‐Saharan Africa and Eurasia, we studied an 8kb segment of the X‐chromosome from 72 chromosomes from the Amhara, Oromo and Ethiopian Jews, and compared these results with 804 chromosomes from Middle Eastern, African, Asian and European populations, and… 
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22 Citations

Ethiopian genetic diversity reveals linguistic stratification and complex influences on the Ethiopian gene pool.

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The analysis of genetic diversity within an 11 kb segment of the MTMR8 gene in a sample of 111 sub-Saharan and 49 non-African X chromosomes revealed a complex genetic structure of the Africans that contributed to the emergence of modern humans, suggestive of a bottleneck in Africa before range expansion.

Regional differences in the distribution of the sub-Saharan, West Eurasian, and South Asian mtDNA lineages in Yemen.

It is concluded that the Yemeni gene pool is highly stratified both regionally and temporally and that it has received West Eurasian, Northeast African, and South Asian gene flow.

The genetic and linguistic structures of Abyssinians and their neighbor reveal the historical demographic dynamics and environmental adaptation in the African Horn region

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An X-linked haplotype of Neandertal origin is present among all non-African populations.

Analysis of 6,092 X-chromosomes from all inhabited continents indicates a very early admixture between expanding African migrants and Neandertals prior to or very early on the route of the out-of-Africa expansion that led to the successful colonization of the planet.

X-chromosome lineages and the settlement of the Americas.

Although genetic drift appears to have played a greater role in the genetic differentiation of Native Americans than in the latitudinally distributed Eurasians, a signal of a differentiated ancestry of southern and northern populations that cannot be simply explained by the serial southward dilution of genetic diversity is observed.

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A complex demographic history and genetic structure of the African melting pot that led to the emergence of modern humans and their out-of-Africa migration is suggested.

Genetic portrait of Jewish populations based on three sets of X-chromosome markers: Indels, Alu insertions and STRs.

African genetic diversity: implications for human demographic history, modern human origins, and complex disease mapping.

This review summarizes patterns and the evolutionary origins of genetic diversity present in African populations, as well as their implications for the mapping of complex traits, including disease susceptibility.

PEOPLE OF GOD, CHILDREN OF HAM

Taxonomies inherited from the nineteenth century have shaped the discourse surrounding the racial identity and supposed roots of Ethiopian immigrants to Israel. Through their interactions with just a…

References

SHOWING 1-10 OF 52 REFERENCES

Extensive female-mediated gene flow from sub-Saharan Africa into near eastern Arab populations.

Analysis of mitochondrial DNA variation of populations from the Near East and Africa and found a very high frequency of African lineages present in the Yemen Hadramawt, consistent with substantial migration from eastern Africa into Arabia, and mainly female assimilation into the Arabian population as a result of miscegenation and manumission.

An anthropogenetic study on the Oromo and Amhara of central Ethiopia

Blood samples from members of the Oromo and Amhara ethnic groups of central Ethiopia were tested for erythrocyte protein systems, consistent with the hypothesis, supported by historical and linguistic evidence, for a common origin of these groups from a Cushitic‐speaking group living in eastern Africa.

Ethiopians and Khoisan share the deepest clades of the human Y-chromosome phylogeny.

The genetic structure of 126 Ethiopian and 139 Senegalese Y chromosomes was investigated by a hierarchical analysis of 30 diagnostic biallelic markers selected from the worldwide Y-chromosome genealogy and confirms the ancestral affinity between the Ethiopians and the Khoisan.

Different genetic components in the Ethiopian population, identified by mtDNA and Y-chromosome polymorphisms.

The hypothesis that the Ethiopian population experienced Caucasoid gene flow mainly through males is proposed, which contains African components ascribable to Bantu migrations and to an in situ differentiation process from an ancestral African gene pool, and exhibits some Y-chromosome affinities with the Tsumkwe San group is discussed.

A back migration from Asia to sub-Saharan Africa is supported by high-resolution analysis of human Y-chromosome haplotypes.

Phylogeographic analyses suggest that a large component of the present Khoisan gene pool is eastern African in origin and that Asia was the source of a back migration to sub-Saharan Africa.

Jewish and Middle Eastern non-Jewish populations share a common pool of Y-chromosome biallelic haplotypes.

The hypothesis that the paternal gene pools of Jewish communities from Europe, North Africa, and the Middle East descended from a common Middle Eastern ancestral population is supported, and most Jewish communities have remained relatively isolated from neighboring non-Jewish communities during and after the Diaspora is suggested.

Confirmation of the Potential Usefulness of Two Human Beta Globin Pseudogene Markers to Estimate Gene Flows to and from Sub-Saharan Africans

The gene frequencies of these two polymorphic sites in nine additional populations are reported, confirming their ethnospecificity and, through the analysis ofThese two markers in Oromo and Amhara of Ethiopia (two mixed populations), their usefulness in genetic admixture studies.

Human X-chromosomal lineages in Europe reveal Middle Eastern and Asiatic contacts

Europe has been influenced by other major population movements, such as expansion(s) from Asia, as well as by recent gene flow from within Europe and the Middle East, which suggests an ancient, bifurcating migration out of Africa that influenced the colonizing of Europe, Asia and the Americas.

Deep common ancestry of Indian and western-Eurasian mitochondrial DNA lineages

Analysis of three RFLPs of the COL1A2 (Type I Collagen) in the Amhara and the Oromo of Ethiopia

The present findings suggest the presence of a differential level of genetic relatedness with south-Saharan peoples in the two Ethiopian groups, which could reflect their different history and seems to indicate the existence of genetic sub-structure within the country.
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