Ethiopia: between Sub‐Saharan Africa and Western Eurasia

@article{Lovell2005EthiopiaBS,
  title={Ethiopia: between Sub‐Saharan Africa and Western Eurasia},
  author={Alan D Lovell and Claudia Moreau and Vania Yotova and F. X. Xiao and St{\'e}phane Bourgeois and Dominik Gehl and Jaume Bertranpetit and Erwin Schurr and Damian Labuda},
  journal={Annals of Human Genetics},
  year={2005},
  volume={69}
}
Ethiopia is central to population genetic studies investigating the out of Africa expansion of modern humans, as shown by Y chromosome and mtDNA studies. To address the level of genetic differentiation within Ethiopia, and its relationship to Sub‐Saharan Africa and Eurasia, we studied an 8kb segment of the X‐chromosome from 72 chromosomes from the Amhara, Oromo and Ethiopian Jews, and compared these results with 804 chromosomes from Middle Eastern, African, Asian and European populations, and… Expand
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Genetic Evidence for Complexity in Ethnic Differentiation and History in East Africa
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The Nyangatom and Daasanach were found to be significantly differentiated, while each of them displays close affinities with some Tanzanian populations, suggesting processes, associated with periods of isolation, could explain the high diversity and strong genetic structure found in East Africa. Expand
X-Linked MTMR8 Diversity and Evolutionary History of Sub-Saharan Populations
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The analysis of genetic diversity within an 11 kb segment of the MTMR8 gene in a sample of 111 sub-Saharan and 49 non-African X chromosomes revealed a complex genetic structure of the Africans that contributed to the emergence of modern humans, suggestive of a bottleneck in Africa before range expansion. Expand
Regional differences in the distribution of the sub-Saharan, West Eurasian, and South Asian mtDNA lineages in Yemen.
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It is concluded that the Yemeni gene pool is highly stratified both regionally and temporally and that it has received West Eurasian, Northeast African, and South Asian gene flow. Expand
The genetic and linguistic structures of Abyssinians and their neighbor reveal the historical demographic dynamics and environmental adaptation in the African Horn region
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A genetic structure analysis of linguistically differentiated populations of Ethiopia, South Sudan, and Somali shows that MKK showed a high genetic diversity comparable to the Ethiopian Cushitic, Semitic, and North Omotic language speakers. Expand
An X-linked haplotype of Neandertal origin is present among all non-African populations.
TLDR
Analysis of 6,092 X-chromosomes from all inhabited continents indicates a very early admixture between expanding African migrants and Neandertals prior to or very early on the route of the out-of-Africa expansion that led to the successful colonization of the planet. Expand
X-chromosome lineages and the settlement of the Americas.
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Although genetic drift appears to have played a greater role in the genetic differentiation of Native Americans than in the latitudinally distributed Eurasians, a signal of a differentiated ancestry of southern and northern populations that cannot be simply explained by the serial southward dilution of genetic diversity is observed. Expand
Tracing genetic history of modern humans using X-chromosome lineages
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A complex demographic history and genetic structure of the African melting pot that led to the emergence of modern humans and their out-of-Africa migration is suggested. Expand
Genetic portrait of Jewish populations based on three sets of X-chromosome markers: Indels, Alu insertions and STRs.
TLDR
X-chromosome analysis and a comparison with autosomal data suggest a generally sex-biased demographic history in Jewish populations, and shows that X-linked markers are highly informative for forensic purposes, and highlight the need for specific databases for differentiated Jewish populations. Expand
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TLDR
This review summarizes patterns and the evolutionary origins of genetic diversity present in African populations, as well as their implications for the mapping of complex traits, including disease susceptibility. Expand
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