Ethionine regulates cell motile activity through LPA receptor-3 in liver epithelial WB-F344 cells

@article{Inoue2013EthionineRC,
  title={Ethionine regulates cell motile activity through LPA receptor-3 in liver epithelial WB-F344 cells},
  author={Serina Inoue and Eriko Tanabe and Ayano Shibata and Miku Hirane and Mutsumi Araki and Yan Yan Dong and Nobuyuki Fukushima and Toshifumi Tsujiuchi},
  journal={Molecular and Cellular Biochemistry},
  year={2013},
  volume={383},
  pages={173-177}
}
Lysophosphatidic acid (LPA) receptors (LPA1 to LPA6) indicate a variety of cellular responses, such as cell proliferation, migration, differentiation, and morphogenesis. However, the role of each LPA receptor is not functionally equivalent. Ethionine, an ethyl analog of methionine, is well known to be one of the potent liver carcinogens in rats. In this study, to assess whether ethionine may regulate cell motile activity through LPA receptors, rat liver epithelial (WB-F344) cells were treated… CONTINUE READING
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