Ethinylestradiol/Drospirenone
@article{Keam2003EthinylestradiolDrospirenone, title={Ethinylestradiol/Drospirenone}, author={Susan J. Keam and Antona J. Wagstaff}, journal={Treatments in Endocrinology}, year={2003}, volume={2}, pages={49-70} }
SummaryAbstractEthinylestradiol 30μg/drospirenone 3mg (Yasmin®1, petibelle®) [EE/DRSP] is a combined contraceptive pill (CC) for the prevention of pregnancy in women of reproductive age. Drospirenone is a novel progestogen with antimineralocorticoid, progestogenic and antiandrogenic activity.The theoretical (0–0.07) and corrected (0.41–0.71) Pearl indices and pregnancy ratios (0.3–0.84) in young, healthy women aged 18–35 years (or 18–30 years if smokers) given 13–26 cycles of EE/DRSP in large…
16 Citations
Drospirenone/Ethinylestradiol 3mg/20µg (24/4 Day Regimen)
- MedicineDrugs
- 2012
Clinical trials indicate that drospirenone/ethinylestradiol 3mg/20µg (24/4) is a good long-term contraceptive option, and additionally offers relief of symptoms that characterise PMDD and has a favourable effect on moderate acne vulgaris.
Pharmacokinetics of drospirenone and ethinylestradiol in Caucasian and Japanese women
- MedicineThe European journal of contraception & reproductive health care : the official journal of the European Society of Contraception
- 2012
Ethnic origin had no clinically relevant influence on the pharmacokinetics of DRSP and EE in Caucasian and Japanese women.
A prospective randomized trial comparing low-dose ethinyl estradiol and drospirenone 24/4 combined oral contraceptive vs. ethinyl estradiol and drospirenone 21/7 combined oral contraceptive in the treatment of hirsutism.
- MedicineContraception
- 2011
Sexual behavior and oral contraception: a pilot study.
- MedicineThe journal of sexual medicine
- 2012
The treatment with Yasmin® (Bayer-Schering Italia) is associated with increased pain during intercourse, with decreased libido and spontaneous arousability, and with diminished frequency of sexual intercourse and orgasm.
Ethinyl Estradiol/Drospirenone for the Treatment of the Emotional and Physical Symptoms of Premenstrual Dysphoric Disorder
- Medicine, BiologyWomen's health
- 2007
A combined oral contraceptive pill containing 20 μg of ethinyl estradiol and 3 mg of the progestin drospirenone in a novel dose regimen has demonstrated efficacy for the symptoms of premenstrual dysphoric disorder, a severe form of prewomen's syndrome, with an emphasis on the affective symptoms.
Oral contraceptives : Does formulation matter ? OCs come in a variety of formulations
- Medicine
- 2013
Whether there are significant differences in effectiveness, cycle control (bleeding), side effects, or satisfaction that may help physicians and patients select the appropriate formulation of oral contraceptive formulations is considered.
Predictable benefits of folate-containing combined oral contraceptives after abortion in women: review
- MedicineGynecology
- 2022
Combined oral contraceptives with 30 mcg ethinyl estradiol in combination with drospirenone can effectively suppress hypothalamic-pituitary-ovarian axis excitability after abortion and folate-containing OCs can be used to prevent neural tube defects in the case of pregnancy after withdrawal of OCs.
Electrochemical immunosensor for ethinylestradiol using diazonium salt grafting onto silver nanoparticles-silica-graphene oxide hybrids.
- Materials ScienceTalanta
- 2016
Scientific Evidences Supporting the Activation of the Renin-Angiotensin-Aldosterone System during Estral Cycle and Pregnancy in Mares
- Biology, MedicineSelected Chapters from the Renin-Angiotensin System
- 2020
In mares, the research team has been investigating the changes of RAAS in mares during the estral cycle and during pregnancy, and these results are presented in the current chapter, comparing with the data previously reported for women and laboratory animals.
A novel and sensitive method for ethinylestradiol quantification in human plasma by high-performance liquid chromatography coupled to atmospheric pressure photoionization (APPI) tandem mass spectrometry: application to a comparative pharmacokinetics study.
- BiologyJournal of chromatography. B, Analytical technologies in the biomedical and life sciences
- 2009
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The combination of 30 g ethinylestradiol/3 mg drospirenone provides effective oral contraception, excellent cycle control, good tolerability and a level of weight loss that may have a significant beneficial effect on compliance in women with a tendency to weight gain due to water retention.
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It is concluded that DHSP may be a suitable partner of ethinyl estradiol as a constituent of an oral contraceptive, since its progestogenic and antialdosterone profile is similar to that of progesterone.
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