Ethical and Practical Issues Associated with Aggregating Databases

Abstract

The goal of “personalized medicine” relies upon defining the genetic variation responsible for disease susceptibility and response to therapy [1]. For most common human diseases, the contribution of a single sequence variant to disease susceptibility is typically small, and can only be detected with data from large numbers of people [2]. Practically, this… (More)
DOI: 10.1371/journal.pmed.0050190

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