Ethical and Policy Issues in Genetic Testing and Screening of Children

@article{Fallat2013EthicalAP,
  title={Ethical and Policy Issues in Genetic Testing and Screening of Children},
  author={Mary E. Fallat and Aviva L. Katz and Mark R. Mercurio and Margaret R. Moon and Alex L. Okun and Sally A. Webb and Kathryn L. Weise and Robert A Saul and Stephen R Braddock and Emily Chen and Debra Freedenberg and Marilyn C. Jones and James M. Perrin and Beth A. Tarini and Karen L David and Louis E. Bartoshesky and Rebecca Rae Anderson and Robert G. Best and Jodi Hoffman and Masamichi Ito and Amy A Lemke and Mitzi L. Murray and Richard R. Sharp and Vikas Bhambhani},
  journal={Pediatrics},
  year={2013},
  volume={131},
  pages={620 - 622}
}
The genetic testing and genetic screening of children are commonplace. Decisions about whether to offer genetic testing and screening should be driven by the best interest of the child. The growing literature on the psychosocial and clinical effects of such testing and screening can help inform best practices. This policy statement represents recommendations developed collaboratively by the American Academy of Pediatrics and the American College of Medical Genetics and Genomics with respect to… 

Tables from this paper

AAP Policy Statement on Genetic Testing and Screening of Children
TLDR
Ethical issues of genetic testing and screening of children need to be considered in the context of the growing literature on the psychological and clinical effects of geneticTesting and screening.
Technical report: ethical and policy issues in genetic testing and screening of children
TLDR
This technical report provides ethical justification and empirical data in support of the proposed policy recommendations regarding genetic testing and screening in a myriad of settings.
Ethical issues in pediatric genetic testing and screening
  • J. Botkin
  • Medicine
    Current opinion in pediatrics
  • 2016
TLDR
The use of microarray and genome sequencing technologies is expanding in the care of children with the notion that the personal utility of test results, rather than clinical utility, may be sufficient to justify testing.
Addressing the Ethical Challenges in Genetic Testing and Sequencing of Children
  • E. Clayton, L. Mccullough, For the Clinical Sequencing Exploratory Research (
  • Medicine
    The American journal of bioethics : AJOB
  • 2014
TLDR
Content analysis of the statements of AAP and ACMG addresses how these recommendations characterize and analyze locus of decision making, as well as the risks and benefits of testing, and whether the guidelines conflict or come to different but compatible conclusions because they consider different testing scenarios.
Genetic testing in children
TLDR
This work attempts to sensitize the caregivers regarding various aspects to be considered before offering any genetic tests in children, and some tests have valid indications with proven benefits over harms while others have less clear justification.
New Guidelines on Genetic Testing and Screening in Children
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This commentary does not contain a discussion of an unapproved/investigative use of a commericial product/device.
Genetic Testing of Children: A Clinical Perspective
It is generally well recognised and accepted that opportunities exist to test individuals for genetic disorders; however, the application of such genetic testing during childhood is subject to
What are the goals of prenatal genetic testing?
TLDR
Prenatal genetic testing must also balance the ethical principles of autonomy and distributive justice, and stakeholders such as medical professionals, professional societies, insurers, commercial laboratories, and the public should consider and come to agreement regarding the appropriate objectives for and use of these tests.
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