Ether‐linked analogue of 2‐arachidonoylglycerol (noladin ether) was not detected in the brains of various mammalian species

  title={Ether‐linked analogue of 2‐arachidonoylglycerol (noladin ether) was not detected in the brains of various mammalian species},
  author={Saori Oka and Akiko Tsuchie and Akira Tokumura and Mayumi Muramatsu and Yoshitomo Suhara and Hiroaki Takayama and Keizo Waku and Takayuki Sugiura},
  journal={Journal of Neurochemistry},
2‐Eicosa‐5′,8′,11′,14′‐tetraenylglycerol (2‐AG ether, HU310, noladin ether) is a metabolically stable ether‐linked analogue of 2‐arachidonoylglycerol (2‐AG), an endogenous cannabinoid receptor ligand. 2‐AG ether has been used as a valuable experimental tool by a number of investigators. Recently, several groups reported that 2‐AG ether is present in mammalian brains. We examined in detail whether 2‐AG ether actually exists in the brains of various mammalian species. We found that 2‐AG ether is… 

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