Ethanolic extraction of bioactive compounds from Vernonia amygdalina leaf using response surface methodology as an optimization tool

@article{Alara2018EthanolicEO,
  title={Ethanolic extraction of bioactive compounds from Vernonia amygdalina leaf using response surface methodology as an optimization tool},
  author={O R Alara and Nour Hamid Abdurahman and Olusegun Abayomi Olalere},
  journal={Journal of Food Measurement and Characterization},
  year={2018},
  volume={12},
  pages={1107-1122}
}
  • O R Alara, Nour Hamid Abdurahman, Olusegun Abayomi Olalere
  • Published in
    Journal of Food Measurement…
    2018
  • Chemistry
  • In this study, ethanolic microwave-assisted extraction of total phenolic content (TFC), total flavonoid content (TFC) and antioxidant from Vernonia amygdalina leaf was investigated using response surface methodology. Four extraction variables, including irradiation time (1‒5 min), microwave power level (500‒700 W), feed-to-solvent ratio (1:8‒1:12 g/ml), and ethanol concentration (60‒80%) were optimized to obtain optimal yields. The analysis of variance results showed that ethanol concentration… CONTINUE READING

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