• Corpus ID: 11517069

Ethanolic extract of Nigella sativa protects Fe(II) induced lipid peroxidation in rat's brain, kidney and liver homogenates.

@article{Hassan2016EthanolicEO,
  title={Ethanolic extract of Nigella sativa protects Fe(II) induced lipid peroxidation in rat's brain, kidney and liver homogenates.},
  author={Waseem Hassan and Hamsa Noreen and S. Khalil and Arshad Hussain and Shakilla Rehman and Shagufta Sajjad and Ataur Rahman and Joao Batista Teixeira da Rocha},
  journal={Pakistan journal of pharmaceutical sciences},
  year={2016},
  volume={29 1},
  pages={
          231-7
        }
}
The study describes the effect of ethanolic extract of Nigella sativa against Fe(II) induced lipid peroxidation. Basal and Fe(II) induced thiobarbituric acid reactive species (TBARS) production was significantly inhibited by the ethanolic extract of Nigella sativa at 25-200 μg/ml. Our data revealed that the extract has high DPPH radical scavenging activity at highest tested concentrations. The extract significantly chelated Fe(II) and scavenged hydroxyl (OH) radical at 25-200μg/ml concentration… 
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