Ethanol selectively attenuates NMDAR-mediated synaptic transmission in the prefrontal cortex.

@article{Weitlauf2008EthanolSA,
  title={Ethanol selectively attenuates NMDAR-mediated synaptic transmission in the prefrontal cortex.},
  author={Carl Weitlauf and John J Woodward},
  journal={Alcoholism, clinical and experimental research},
  year={2008},
  volume={32 4},
  pages={690-8}
}
BACKGROUND Brain imaging studies have revealed abnormal function in the prefrontal cortex (PFC) of alcoholics that may contribute to the impulsive behavior and lack of control over drinking that characterizes this disorder. Understanding how ethanol affects the physiology of PFC neurons may help explain this loss of control and lead to better treatments for alcohol addiction. In a previous study from this laboratory, we showed that ethanol inhibits complex patterns of persistent activity (known… CONTINUE READING
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