Ethanol oxidation by a component of liver microsomes rich in cytochrome P-450.

  title={Ethanol oxidation by a component of liver microsomes rich in cytochrome P-450.},
  author={Esteban Mezey and James John Potter and W. D. C. Reed},
  journal={The Journal of biological chemistry},
  volume={248 4},

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Purified preparations of rat liver microsomes consist of flat discoid structures, presumably vesicles, which catalyze oxidation of ethanol to acetaldehyde in the absence of alcohol dehydrogenase and catalase, and the activity of the microsomal ethanol- oxidizing system was increased significantly, confirming the enzymic nature of the reaction studied.
Ethanol oxidation by components of rat liver microsomes.


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