Ethanol modulation of GABAergic transmission: the view from the slice.

  title={Ethanol modulation of GABAergic transmission: the view from the slice.},
  author={J. L. Weiner and C F Valenzuela},
  journal={Pharmacology & therapeutics},
  volume={111 3},
For almost three decades now, the GABAergic synapse has been the focus of intense study for its putative role in mediating many of the behavioral consequences associated with acute and chronic ethanol exposure. Although it was initially thought that ethanol interacted solely with the postsynaptic GABAA receptors that mediate the majority of fast synaptic inhibition in the mammalian central nervous system (CNS), a number of recent studies have identified novel pre- and postsynaptic mechanisms… CONTINUE READING

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