Ethanol ingestion increases susceptibility of mice to Listeria monocytogenes.

  title={Ethanol ingestion increases susceptibility of mice to Listeria monocytogenes.},
  author={Amina Saad and R Domiati-Saad and Thomas R. Jerrells},
  journal={Alcoholism, clinical and experimental research},
  volume={17 1},
Excessive consumption of alcohol is associated with an increase in the frequency and severity of infectious diseases. Ethanol adversely affects specific and nonspecific aspects of the immune response. We used a murine model to determine whether ethanol ingestion impairs host mechanisms of resistance to Listeria monocytogenes. Naive mice and mice immune to L. monocytogenes were pair-fed either a Leiber-DeCarli liquid diet containing 7% (v/v) ethanol or an isocaloric control diet for 7 days. Then… CONTINUE READING
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