Ethanol-induced inhibition of GABA release from LS and SS mouse brain slices.

@article{Howerton1984EthanolinducedIO,
  title={Ethanol-induced inhibition of GABA release from LS and SS mouse brain slices.},
  author={Thomas C. Howerton and Allan C. Collins},
  journal={Alcohol},
  year={1984},
  volume={1 6},
  pages={
          471-7
        }
}
The effects of ethanol on K+-stimulated and spontaneous release of gamma-aminobutyric acid (GABA) were studied in cortical and cerebellar brain slices obtained from long-sleep (LS) and short-sleep (SS) mice. A superfusion technique was used. Tissue slices were perfused with ethanol (0-515 mM) for 20 min. Ethanol inhibited K+-stimulated 3H-GABA release at lower concentrations in LS cortical slices than in SS slices. Little or no inhibition of K+-stimulated 3H-GABA release was seen in both LS and… CONTINUE READING