Ethanol-induced conditioned taste aversion in BXD recombinant inbred mice.

  title={Ethanol-induced conditioned taste aversion in BXD recombinant inbred mice.},
  author={F O Risinger and Christopher L. Cunningham},
  journal={Alcoholism, clinical and experimental research},
  volume={22 6},
Genetic differences in sensitivity to ethanol's aversive effects may play an important role in the development of alcohol-seeking behavior and alcoholism. The present study examined the development of ethanol-induced conditioned taste aversion in 20 BXD/Ty recombinant inbred strains of mice and their progenitor inbred strains, C57BL/6J (B6) and DBA/2J (D2). Adult male mice were given 1-hr access to a saccharin-flavored solution every 48 hr for 12 days. After all but the first and last saccharin… CONTINUE READING
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