Ethanol increases receptor-dependent cyclic AMP production in cultured hepatocytes by decreasing G(i)-mediated inhibition.

Abstract

Increasing evidence suggests that ethanol-induced changes in cyclic AMP (cAMP) signal transduction play a critical role in the acute and chronic effects of ethanol. Here we have investigated the effects of ethanol on cAMP signal transduction in primary cultures of rat hepatocytes. Acute exposure to ethanol had a biphasic effect on glucagon-receptor… (More)

Topics

Cite this paper

@article{Nagy1992EthanolIR, title={Ethanol increases receptor-dependent cyclic AMP production in cultured hepatocytes by decreasing G(i)-mediated inhibition.}, author={Lee Nagy and Shani Desilva}, journal={The Biochemical journal}, year={1992}, volume={286 ( Pt 3)}, pages={681-6} }