Ethanol increases endothelial nitric oxide production through modulation of nitric oxide synthase expression.

@article{Venkov1999EthanolIE,
  title={Ethanol increases endothelial nitric oxide production through modulation of nitric oxide synthase expression.},
  author={C. Venkov and P. R. Myers and M. Tanner and M. Su and D. Vaughan},
  journal={Thrombosis and haemostasis},
  year={1999},
  volume={81 4},
  pages={
          638-42
        }
}
Moderate alcohol consumption has been shown to reduce the risk of ischemic heart disease potentially through its effect on specific endothelial-derived compounds. We tested the hypothesis that ethanol increases the expression of endothelial nitric oxide synthase (eNOS) and nitric oxide (NO) production in bovine aortic endothelial cells (BAEC). Primary cultures of BAEC grown to confluence under standard conditions were treated 3-6 h with 0.1% ethanol in the presence of indomethacin. Ethanol… Expand
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