Ethanol enhances the functional recovery of stunned myocardium independent of K(ATP) channels in dogs.

@article{Gross2001EthanolET,
  title={Ethanol enhances the functional recovery of stunned myocardium independent of K(ATP) channels in dogs.},
  author={Eric R. Gross and Meir Gare and Wolfgang G Toller and Judy R. Kersten and David C. Warltier and P S Pagel},
  journal={Anesthesia and analgesia},
  year={2001},
  volume={92 2},
  pages={299-305}
}
Chronic, intermittent exposure to small amounts of ethanol reduces myocardial infarct size in vivo. We tested the hypothesis that acute administration of ethanol enhances the functional recovery of stunned myocardium and that adenosine triphosphate-dependent potassium (K(ATP)) channels mediate this beneficial effect. Barbiturate-anesthetized dogs were instrumented for measurement of aortic and left ventricular pressure, +dP/dt(max), and subendocardial segment shortening (%SS) and were subjected… CONTINUE READING
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