Ethanol and acetaldehyde alter brain mitochondrial redox responses to direct cortical stimulation in vivo

@article{Novack1982EthanolAA,
  title={Ethanol and acetaldehyde alter brain mitochondrial redox responses to direct cortical stimulation in vivo},
  author={Roger L. Novack and Joseph C. LaManna and Myron Rosenthal},
  journal={Neuropharmacology},
  year={1982},
  volume={21},
  pages={1051-1058}
}
To determine whether and how ethanol and acetaldehyde alter brain oxidative metabolic activity, reduction/oxidation shifts of components of the mitochondrial respiratory chain were optically measured, in situ, from cat cerebral cortex. Oxidative shifts of nicotinamide adenine dinucleotide (NADH) were recorded in response to increased energy demand provoked by stimulation of the cortical surface by electrical pulses. Ethanol or acetaldehyde did not alter the direction of the responses but each… CONTINUE READING